Much of the initial breeding work held at CICA was thus to adapt the Barberton varieties to local ecological conditions by using selections of the U4 strain aiming to enhance productivity and the technological properties of the fiber. A constant selection effort was also necessary to avoid the degeneration of the cultivated varieties resulting from crossings with previously planted varieties by insect pollination or poor seed isolation, in order to keep the good properties of yield, fiber quality, and resistance to diseases or plagues. Each of the regional experiment stations, controlled by the Research Center, performed essays testing different selected seeds under different conditions of fertilization, pest control, sowing timing or rotation of cultures. Until the CICA began to operate in Mozambique, the U4 seeds were imported from South Africa, with two big deliveries in 1937 and 1940.[113] In subsequent years, in addition to imports from Barbeton as well as from Namulonge in Uganda, CICA breeders released their own strains from selections of the British Empire ones, produced in the several experimental fields operated throughout the territory. Beginning with a overwhelming presence of the U4 in the 1940s, maps produced by CICA researchers for the different regions showed in subsequent years many other strains: A618, A637, A455, SB8, and so on, each of them chosen in function of different local conditions. The big challenge was to increase the length of the fiber produced without diminishing resistance to Jassid. In fact, maps were also produced that showed the quality of the fiber produced in each area of cotton cultivation as measured by their micronaire index (air permeability of compressed cotton fibers which indicates fiber fineness and maturity).[114] The entire territory was now translated in function of the regional variations of the technological index of the cotton fiber.
Not only did Quintanilha supervise everyone’s work; his cytogenetic knowledge wasn’t wasted. He assembled a major collection of cotton varieties in the facilities of CICA and surveyed the Mozambican countryside in search for more.[115] He was able to demonstrate that, contrary to what botanists had believed, not only was there no presence of the species