“Never, not him. Either closemouthed or asking too many questions, nothing in between. Not sociable either. You might say that the only friend he had was his computer. You would think he would have had enough of that during school hours. All computerized now, you know. But no. As soon as he was home he would be right at it again. Not just games, but writing programs in LOGO, the language he had learned in school. Very good programs too, that’s what Paddy said. The boy was writing learning programs that wrote their own programs. There was always something special between Brian and computers.”
5
February 18, 2023
Benicoff was waiting when Snaresbrook came out of the operating room.
“Do you have a moment to spare, Doctor?”
“Yes, of course. You can tell me what is happening at your end…”
“Can we continue this in your office?”
“Good idea. I have a new coffee machine that I want to try out. It just arrived and was installed this morning.”
Benicoff closed the office door, then turned and raised his eyebrows at the brass machine. “I thought you said new?”
“New to me, that is. This gorgeous device must be ninety years old if it is a day. They just don’t make them this way anymore.”
“With good reason!”
It was six feet high, an impressive gleaming array of valves, pipes, riveted plates, cylinders--all of which was crowned by a bronze eagle with wide-spread wings. Steam hissed loudly from a protruding pipe when Dr. Snaresbrook twisted a knob. “Espresso or cappuccino?” she asked, loading fragrant black coffee into the black-handled holder.
“Espresso — with a twist of lemon.”
“I can see that you have been around. That’s the only way to drink it. Is there any news on the thieves?”
“Negative — but a hard-worked negative. The FBI, the police and a dozen agencies have kept this investigation going night and day. Every possible lead has been followed, every detail of that night’s events investigated exhaustively. Yet there’s not a thing discovered worth mentioning since I talked to you last. That’s good coffee.” He sipped again and waited until Snaresbrook had made one of her own. “And that, I am sorry to say, is all that I have to report. I hope you have better news about Brian.”
Erin Snaresbrook stared into the steaming dark liquid; stirred in another spoonful of sugar. “Basically the good news is that he is still alive. But the severed nerves deteriorate more every day. I’m racing against time — and I don’t know yet if I am winning or losing. As you know, after a nerve fiber dies, a sort of empty tube remains. That was why I have implanted fetal brain cells to grow and replace those fibers. The manipulating machine will also inject tiny amounts of the nerve growth drug gamma-NGF to induce the fetal cells’ axons to grow down those tubes. This technique was discovered in the 1990s by researchers looking for a way to repair spinal-cord injuries — they used to always result in permanent paralysis. Now we repair brain injuries by using this and another drug, SRS, that overcomes the tendency of mature brain cells to resist invasion by other nerve fibers trying to make new connections.”
Benicoff frowned. “Why would brains do such a thing, if it keeps them from repairing themselves?”
“An interesting question. Most other body tissues are very good at making repairs, or admitting other cells that offer help. But think for a moment about the nature of a memory. It is based on the precise relations of unbelievably tiny fiber connections. Once those connections are made, they have to persist, with almost no change, for twenty, or fifty, or even ninety years! Therefore the brain has evolved many peculiar defenses of its own, defenses found in no other tissue, to prevent most normal kinds of change. It appears that the advantage of having better memory outweighs the advantage of being able to repair injury.
“Brian’s recovery is going to take some time. The slowest part of the process will be regrowing the severed nerve fibers. That will require at least a few months, even using NGF, since we don’t dare to use it in large doses. NGF causes uninjured brain cells to grow as well — which if not monitored closely will disrupt the parts of the brain that still work! To say nothing of the risk of cancer. Because of this, Brian’s progress will be very slow.”
“Will you be proceeding with this process now?”
“Not at once, not until the new nerve fibers have grown. When that has happened we will have to find out what the brain cells do on each side of the injury. When we have sorted that out, we can think about reconnecting the correct pairs.”
“But there must be millions of them!”