Coma

“It’s all right now,” said Dr. Billing, pulling his anesthesia machine close to Nancy’s head. With well-rehearsed adeptness, he attached his Pentothal syringe to the three-way valve on the I.V. line. “Now I want you to count to fifty for me, Nancy.” He expected that Nancy would never get past fifteen. In fact, it gave Dr. Billing a certain sense of satisfaction to watch the patient go to sleep. It represented repetitive proof for him of the validity of the scientific method. Besides, it made him feel powerful; it was as if he had command of the patient’s brain.

Nancy was a strong-willed individual, however, and although she wanted to go to sleep, her brain involuntarily fought against the drug. She was still audibly counting when Dr. Billing gave an additional dose of Pentothal. She said twenty-seven before the two grams of the drug succeeded in inducing sleep. Nancy Greenly fell asleep at 7:24 on February 14, 1976, for the last time.

Dr. Billing had no idea this healthy young woman was going to be his first major complication. He was confident that everything was under control The list was almost complete. He had Nancy breathe a mixture of halothane, nitrous oxide, and oxygen through a mask. Then he injected 2

cc’s of a 0.2 percent succinylcholine chloride solution into Nancy’s I.V. to effect a paralysis of all her skeletal muscles. This would make the placement of the endotracheal tube in the trachea easier. It would also allow Dr. Major to perform a bimanual exam, to rule out ovarian pathology.

The effect of the succinylcholine was seen almost immediately. At first there were minute fasciculations of the muscles of the face, then the abdomen. As the bloodstream sped the drug throughout the body, the motor and end plates of the muscles became depolarized, and total paralysis of the skeletal muscles occurred. Smooth muscles, like the heart, were unaffected, and the beep from the monitor continued without a waver.

Nancy’s tongue was paralyzed and it fell back, blocking her airway. But that didn’t matter. The muscles of the thorax and abdomen were paralyzed as well, and any attempt at breathing ceased. Although chemically different from the curare of the Amazon savages, the drug had the same effect, and Nancy would have died in five minutes. But at this point nothing was wrong. Dr. Billing was in total control. The effect was expected and desirable. Outwardly calm, inwardly very tense, Dr.

Billing put down the breathing mask and reached for the laryngoscope, step number 22 on his list With the tip of the blade, he pulled the tongue forward and maneuvered past the white epiglottis, while he visualized the entrance to the trachea. The vocal cords were ajar, paralyzed with the rest of the skeletal muscles.

Swiftly Dr. Billing squirted some topical anesthetic into the trachea, followed by the endotracheal tube. The laryngoscope made a characteristic metallic snap as Dr. Billing folded the blade onto the handle. With the help of a small syringe, he inflated the cuff on the endotracheal tube, providing a seal. Quickly he attached the tip of the rubber hose, without the face mask, to the open end of the endotracheal tube. As he compressed the ventilating bag, Nancy’s chest rose in a symmetrical fashion. Dr. Billing listened to Nancy’s chest with his stethoscope and was pleased. The entubation had been as characteristically smooth as expected. He was in total control of the patient’s respiratory state. He adjusted his flow meters and set the combination of halothane, nitrous oxide, and oxygen he wanted. A few pieces of tape secured the endotracheal tube. A twist of the finger adjusted the I.V. rate. Dr. Billing’s own heart began to slow down. He never showed it, but he always got very tense during the entubation procedure. With the patient paralyzed one has to work fast, and do it right.

With a nod, Dr. Billing indicated that Gloria, D’Mateo could begin the prep of Nancy’s shaved perineum. Meanwhile Dr. Billing began to make himself comfortable for the case. His job was now reduced to close observation of the patient’s vital signs: heart rate and rhythm, blood pressure, and temperature. As long as the patient was paralyzed, he had to compress the ventilating bag, to breathe the patient The succinylcholine would wear off in eight to ten minutes; then the patient could breathe herself, and the anesthesiologist could relax. Nancy’s blood pressure stayed at 105/70. The pulse had steadily fallen from the anxiety state prior to anesthesia to a comfortable seventy-two beats per minute. Dr. Billing was happy, and he looked forward to a coffee break in about forty minutes.